Capsule Shields the Function of Short Bacterial Adhesins

Capsule shields the function of short bacterial adhesins.

Bacterial surface structures such as capsules and adhesins are generally regarded as important virulence factors. Here we demonstrate that capsules block the function of the self-recognizing protein antigen 43 through physical shielding. The phenomenon is not restricted to Escherichia coli but can occur in other gram-negative bacteria. Likewise, we show that other short adhesins exemplified by ...

Structural biology of Gram-positive bacterial adhesins.

The structural biology of Gram-positive cell surface adhesins is an emerging field of research, whereas Gram-negative pilus assembly and anchoring have been extensively investigated and are well understood. Gram-positive surface proteins known as MSCRAMMs (microbial surface components recognizing adhesive matrix molecules) and individual proteins that assemble into long, hair-like organelles kn...

PART I Bacterial adhesins and adhesive structures

Sticky fibers and uropathogenesis: bacterial adhesins in the urinary tract.

Adhesins mediate the introduction of bacteria to the host in the sometimes life-long relationship of uropathogenic Esherichia coli (UPEC) and the human urinary tract. As a class of extracellular proteins, adhesins enable bacteria to adhere to and, in some cases, invade host tissue; adhesins render UPEC virulent and permit host colonization. Adhesin receptor interactions at the host interface de...

rehabilitation of the oral function of edentulous patient by implants توانبخشی کارکرد خوراک در بیماران بی دندان توسط ایمپلنت

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